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Coelenterazine-WS

Item # Unit Size
C397-10
1 mg (Coelenterazine content: 2%)

For Research Use Only Products

MSDS
Chemical Name: Coelenterazine, β-cyclodextrin complex

Appearance:
pale yellowish-brown powder
Solubility (in 0.1 mol/l phosphate buffer): To pass test (clear, slightly yellow)


Storage Condition: -20ºC, protect from light and moisture
Shipping Condition:
blue ice

Product Description
Aequorin is a luminescent protein that contains coelenterazine as a luminescent compound. Since aequorin emits luminescence by calcium conjugation, it is used for intracellular calcium ion detection. However, coelenterazine has poor water solubility under physiological conditions, and it is adsorbed to cell membranes. Dojindo’s Coelenterazine-WS is a β-cyclodextrin complex of coelenterazine with drastically improved water solubility at neutral pH.

Chemical Structure


References
1. K. Teranishi, et al., Solubilizing Coelenterazine in Water with Hydroxypropyl-β-cyclodextrin. Biosci Biotech Biochem. 1997;61:1219-1220.