Cell Based Assay

Cell viability and cytotoxicity assays are used for drug screening and cytotoxicity tests of chemicals. Dojindo developed highly water-soluble tetrazolium salts called WSTs. WST-8, a highly stable WST, is utilized in Cell Counting Kit-8 (CCK-8). Since WST-8 formazan is water soluble, it does not form crystals. Therefore, solubilizing process such as MTT assay is not required. Additionally, The detection sensitivity of CCK-8 is higher than the other tetrazolium salts such as MTT, XTT, MTS or WST-1.