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2,3-Diaminonaphthalene (for NO detection) 2,3-Diaminonaphthalene (for NO detection), 2,3-Diaminonaphthalene [CAS: 771-97-1]
Item #: D418 -

Product Description The Griess assay is a simple and popular method for detecting NO concentration. 2,3-Diaminonaphthalene (DAN) is a highly sensitive alternative to the Griess assay. The DAN method is 50-100 times more sensitive than the Griess assay: While the detection limit of the Griess assay is 1 mM, the limit of the DAN method is 10-50 nM. DAN reacts with NO2- in acidic conditions to produce fluorescent naphthalenetriazole. The wavelength of the emission maximum of naphthalenetriazole...

Carboxy-PTIO Carboxy-PTIO, 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, sodium salt [CAS: 148819-93-6]
Item #: C348 -

Product DescriptionCarboxy-PTIO is a stable, water-soluble organic radical that reacts with NO to form NO2· This reaction can be monitored by electron spin resonance (ESR). NO is an unstable molecule and has a complex reaction cascade for its metabolism in biological systems. Rapidly generated NO-related metabolites carry out various physiological activities. Commonly used NO scavengers such as hemoglobin trap NO; they also trap NOS inhibitors such as arginine derivatives. These NO scavengers...

DTCS Na DTCS Na, N-(Dithiocarboxy)sarcosine, disodium salt, dihydrate [CAS: 13442-87-0]
Item #: D465 -

Product Description Diethyldithiocarbamate (DETC) is a good spin-trapping reagent for nitric oxide in vivo. However, DETC has not been widely utilized for NO detection in biological samples due to its poor water solubility. DTCS, an analog of DETC, forms a water-soluble iron(II) complex (Fe-DTCS). The Fe-DTCS complex then forms a complex with NO (NO-Fe-DTCS). Dr. Yoshimura successfully obtained two-dimensional ESR images of NO, induced by lipopolysaccharide in mouse peritoneum. DTCS sodium...