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2,3-Diaminonaphthalene (for NO detection) 2,3-Diaminonaphthalene (for NO detection), 2,3-Diaminonaphthalene [CAS: 771-97-1]
Item #: D418 -

Chemical Name: 2,3-Diaminonaphthalene CAS: 771-97-1Appearance: White or pale yellowish-brown powderSuitability for NO quantification: pass testMW: 158.20, C10H10N2Storage Condition: -20ºC, protect from lightShipping Condition: ambient temperatureProduct DescriptionThe Griess assay is a simple and popular method for detecting NO concentration. 2,3-Diaminonaphthalene (DAN) is a highly sensitive alternative to the Griess assay. The DAN method is 50-100 times more sensitive than the Griess assay:...

2-PDS 2-PDS, 2,2’-Dithiodipyridine [CAS: 2127-03-9]
Item #: P016 -

Chemical Name: 2,2'-Dithiodipyridine CAS: 2127-03-9Appearance: white or pale yellow powderMolar absorptivity: ≥14,000 at 235 nmMW: 220.32, C10H8N2S2Storage Condition : ambient temperatureShipping Condition : ambient temperature Fig 1. 2-PDS reaction with thiol compound ...

3-Deoxyglucosone 3-Deoxyglucosone, 3-Deoxy-D-erythro-hexos-2-ulose [CAS: 4084-27-9]
Item #: D535 -

Chemical Name: 3-Deoxy-D-erythro-hexos-2-ulose CAS: 4084-27-9Appearance: white or pale yellow solidPurity: ≥99.0% (HPLC)MW: 162.14, C6H10O5Storage Condition: -20°CShipping Condition: protect from moisture with blue ice or dry iceProduct DescriptionAdvanced glycation end-products (AGEs) have been studied as one of the causes of diabetic complications. Several compounds have been identified as AGEs, including pyralline, pentosidine, imidazolone, and pyropyridine. Glyoxal and methylglyoxal are...

4-PDS 4-PDS, 4,4’-Dithiodipyridine [CAS: 2645-22-9]
Item #: P017 -

Chemical Name: 4,4'-Dithiodipyridine CAS: 2645-22-9Appearance: white or pale yellow powderMolar absorptivity: ≥14,000 at 235 nmMW: 220.32, C10H8N2S2 Storage Condition : ambient temperatureShipping Condition: ambient temperature Product Description2-PDS and 4-PDS are used for the photometric determination of thiol groups in biological samples. These compounds react with the thiol groups at pH 5 to form mercaptopyridine (Fig. 1 and 2). The maximum wavelengths of 2-Mercaptopyridine and...

BMPO BMPO, 5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide
Item #: B568 -

Chemical Name: 5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide  Appearance: White to slightly yellowish white crystal or crystalline powderPurity: ≥99.0%MW: 199.25, C10H17NO3Storage condition: -20°C, protect from moisture  Shipping condition: ambient temperatureChemical StructureProduct Description Spin trapping analysis is one of the most reliable techniques for detecting and identifying short-lived free radicals. The EPR (ESR) spin trap reagent detects both superoxide and...

Carboxy-PTIO Carboxy-PTIO, 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, sodium salt [CAS: 148819-93-6]
Item #: C348 -

Chemical Name: 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, sodium salt CAS: 148819-93-6Appearance: Dark blue or black powderMW: 299.28, C14H16N2NaO4Storage Condition: -20ºC, protect from light, moisture and metal Shipping Condition: ambient temperatureProduct DescriptionCarboxy-PTIO is a stable, water-soluble organic radical that reacts with NO to form NO2· This reaction can be monitored by electron spin resonance (ESR). NO is an unstable molecule and has a...

Cellular Senescence Detection Kit - SPiDER-ßGal Cellular Senescence Detection Kit - SPiDER-ßGal, SG03, SG03-10,
Item #: SG03 -

Technical Manual Supplemental Manual Kit content (1 plate) : SPiDER-βGal x 1, Bafilomycin A1 x 1 Storage Condition : 0-5oC Shipping Condition : ambient temperature Product Description Simple Procedure Applicable for Living and Fixed Cells Detection with Flow Cytometry Markers of Senescent Cells Co-staining with DNA Damage marker: Live cells Co-staining with DNA Damage marker: Fixed cells Confocal Quantitative Image Cytometer Recommended Filter Product Description DNA damages of the normal...

Cellular Senescence Plate Assay Kit - SPiDER-ßGal Cellular Senescence Plate Assay Kit - SPiDER-ßGal, SG05, SG05-01,SG05-05
Item #: SG05 -

Product Manual (SG05) Protocol for Combined Analysis (SG05 and C544) Kit contents : Storage Condition : 0-5oC Shipping Condition : ambient temperature Description: This product is a simple detection kit by plate assay for senescence-associated β-galactosidase (SA-β-gal) activity which is used as a marker for senescent cells. By simply adding SPiDER-βGal, a reagent for detection of β-galactosidase, to 96 well plates, this kit allows you to quantify SA-β-gal activity and makes it possible to...

DALGreen - Autophagy Detection DALGreen - Autophagy Detection, D675, MD01, SG03, CK04, CK12
Item #: D675 -

Content : 20 nmol x 1 Storage conditions : Store at -20oC and protect from light Shipping conditions : Ambient Temperature Product Description Simple Procedure Procedure Comparison between DALGreen and Existing Reagents Comparison to LC3 Comparison to MDC Time-lapse imaging of autophagy The Number of Usable Assay Usage example of publications References Product Description DALGreen is used to detect autophagy in live cells. Autophagy is an intracellular degradation system, where dysfunctional...

DMPO DMPO, Purity, High Purity, 3317-61-1
Item #: D048 -

Chemical Description: 5,5-Dimethyl-1-Pyrroline-N-OxideCAS: 3317-61-1Appearance: Colorless liquidPurity: ≥99.0%(GC)MW: 113.16, C6H11NOStorage Condition: -20oC, protect from light and moisture Shipping Condition: Blue Ice Product Description Because of potential cancer risks and their age-promoting effects, free radicals in living bodies have become a frequently studied subject. DMPO is the most frequently used spin-trapping reagent for the study of free radicals. It is suitable for...

DNA Damage Quantification Kit-AP Site Counting- DNA Damage Quantification Kit-AP Site Counting-, ROS, Oxdative stress, Comet assay,  Genomic DNA, 8-OHdG, Abasic site, Hydroxy radical, Aldehyde reactive probe, ARP, DNA repair
Item #: DK02 -

Contents of the Kit ARP Solution  :250 μl x 1 tube      DNA Binding Solution  :10 ml x 1 bottle  ARP-DNA Standard Solution :250 μl each Substrate Solution :10 ml x 1 bottle Filtration Tube :20 tubes TE Buffer :40 ml x 1 bottles Washing Buffer :1 packet  HRP-Streptavidin :25 μl x 1 tubes 96-well Microplate :1 plate     Storage Condition: 0-5ºCShipping Condition: ambient temperature or with blue iceRequired Equipment and Materialsmicroplate reader...

DPPP DPPP, Diphenyl-1-pyrenylphosphine [CAS: 110954-36-4]
Item #: D350 -

Chemical Name: Diphenyl-1-pyrenylphosphine CAS: 110231-30-6Appearance: slightly yellow powderPurity: ≥97% (HPLC)MW: 386.42, C28H19PStorage Condition : ambient temperature, protect from lightShipping Condition: ambient temperatureProduct DescriptionDPPP is a non-fluorescent triphenylphosphine compound. It reacts with hydroperoxide to generate DPPP oxide that emits fluorescence at 352 nm excitation and 380 nm emission wavelengths (Fig. 1). Post-column HPLC method is used to determine...

DTCS Na DTCS Na, N-(Dithiocarboxy)sarcosine, disodium salt, dihydrate [CAS: 13442-87-0]
Item #: D465 -

Chemical Name: N-(Dithiocarboxy)sarcosine, disodium salt, dihydrate CAS: 13442-87-0Appearance: White or slightly yellow powderMW: 245.23, C4H5NNa2O2S2, 2H2OStorage Condition: 0-5ºC, protect from light and moisture Shipping Condition: ambient temperatureProduct DescriptionDiethyldithiocarbamate (DETC) is a good spin-trapping reagent for nitric oxide in vivo. However, DETC has not been widely utilized for NO detection in biological samples due to its poor water solubility. DTCS, an analog...

DTNB DTNB, 5,5’-Dithiobis(2-nitrobenzoic acid) [CAS: 69-78-3]
Item #: D029 -

Chemical Name: 5,5'-Dithiobis(2-nitrobenzoic acid)CAS: 69-78-3Appearance: pale yellow crystalline powderMolar absorptivity: ≥12,000 at 305 nmMW: 396.35, C14H8N2O8S2 Storage Condition : ambient temperatureShipping Condition: ambient temperature Product DescriptionDTNB is known as Ellman’s reagent. It is used for the colorimetric determination of thiol groups in biological samples. It is fairly soluble in water. Colorless DTNB is converted to yellow 5-Mercapto-2- nitrobenzoic acid in the...

GSSG/GSH Quantification Kit Glutathione,  GSSG/GSH Quantification Kit
Item #: G257 -

Storage Condition : 0-5oC, protect from lightShipping Condition :  blue iceProduct DescriptionGlutathione (γ-L-glutamyl-L-cysteinylglycine) is a tripeptide present in the body, and it is involved in antioxidation, drug metabolism, and other as enzyme substrate of glutathione peroxidase, glutathione S-transferase, and thiol transferase, etc. Glutathione is usually present as reduced form (GSH), but GSH is converted into its oxidized form (GSSG) by stimulation such as oxidative stress....

Liperfluo Lipid peroxide imaging is available by a fluorescence microscopy and a flow cytometric analysis for living cells.
Item #: L248 -

Product Description Liperfluo, a perylene derivative containing oligooxyethylene, is designed and exclusively developed by Dojindo for the detection of lipid peroxides. Liperfluo emits intense fluorescence by lipid peroxide specific oxidation in organic solvents such as ethanol. Among fluorescent probes that detect Reactive Oxygen Species(ROS), Liperfluo is the only compound that can specifically detect lipid peroxides. Since the excitation and emission wavelengths of the oxidized Liperfluo...

MitoPeDPP autophagy, mitochondria, Lipid peroxide, Lipid peroxidation, ROS imaging, TBA, TBARS
Item #: M466 -

Chemical Name: 3-[4-(Perylenylphenylphosphino)phenoxy]propyltriphenylphosphonium iodide Appearance:  Purity: ≥80.0% (HPLC) MW: 882.74, C53H41IOP2 Storage Condition: 0-5ºC, protect from light Shipping Condition: ambient temperature Product Description MitoPeDPP is a cell-membrane-permeable probe, Perylene-based dye. It specifically localizes in mitochondria due to the triphenylphosphonium moiety introduced. As the excitation and emission wavelength of MitoPeDPP are 452 nm and 470...

Mitophagy Detection Kit MD01, MD01-10, Mitophagy Detection Kit
Item #: MD01 -

Mitophagy Detection Kit Mtphagy Dye Product Description Simple Procedure: Just Add Mtphagy Dye Comparison with Autophagy Marker Mitophagy Detection in Starved Cells Experimental Example: Induction of Mitophagy by CCCP Mitophagy Induction and Detection of Mitochondrial Membrane Potential Changes Product Description Mitophagy Detection Kit is optimized for mammalian cells. Mitochondria is one of the cytoplasmic organelle that plays a crucial role in cells such as production of energy for cell...

NOC 12 NOC 12, 1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazene [CAS: 146724-89-2]
Item #: N378 -

Chemical Name: 1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazeneCAS: 146724-89-2Appearance: White powderPurity: ≥90% (HPLC)MW: 176.22, C6H16N4O2Storage Condition : -20ºC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC....

NOC 18 NOC 18, 1-Hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene [CAS: 146724-94-9]
Item #: N379 -

Chemical Name: 1-Hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazeneCAS: 146724-94-9Appearance: White powderPurity: ≥90% (HPLC)MW: 163.18, C4H13N5O2Storage Condition : -20ºC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism...

NOC 5 NOC 5, 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene [CAS: 146724-82-5]
Item #: N380 -

Chemical Name: 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene CAS: 146724-82-5Appearance: White powderPurity: ≥90% (HPLC)MW: 176.22, C6H16N4O2Storage Condition : -20ºC, protect from light and moistureShipping Condition : blue iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism...

NOC 7 NOC 7, 1-Hydroxy-2-oxo-3-(N-methyl-3-aminopropyl)-3-methyl-1-triazene [CAS: 146724-84-7]
Item #: N377 -

Chemical Name: 1-Hydroxy-2-oxo-3-(N-methyl-3-aminopropyl)-3-methyl-1-triazene CAS: 146724-84-7Appearance: white powderPurity:≥90% (HPLC)MW: 162.19, C5H14N4O2Storage Condition : -20oC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC....

NOR 3 NOR 3, (+)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide [CAS: 163180-49-2]
Item #: N390 -

Chemical Name: (+)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide CAS: 163180-49-2Appearance: White crystalline powderPurity: ≥98.0% (HPLC)MW: 215.21, C8H13N3O4Storage Condition : -20ºC, protect from light and moistureShipping Condition : ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety, they spontaneously...

NOR 5 NOR 5, (+)-N-{(E)-4-Ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-heptenyl}-3-pyridinecarboxamide
Item #: N448 -

Chemical Name: (+)-N-{(E)-4-Ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-heptenyl}-3-pyridinecarboxamideAppearance: White or slightly yellow powderPurity: ≥98.0% (HPLC)MW: 334.37, C16H22N4O4Storage Condition : -20ºC, protect from light and moistureShipping Condition : ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety,...

S-Nitrosoglutathione S-Nitrosoglutathione, N-(N-L-?-Glutamyl-S-nitroso-L-cysteinyl)glycine [CAS: 57564-91-7]
Item #: N415 -

Chemical Name: N-(N-L-γ-Glutamyl-S-nitroso-L-cysteinyl)glycine CAS: 57564-91-7Appearance: Pink powderPurity: ≥90.0% (HPLC)MW: 336.32, C10H16N4O7SStorage Condition: -20ºCShipping Condition: protect from moisture ambient temperatureReaction of NO releaseProduct Description of S-NitrosothiolsNitrosothiol compounds release NO and become disulfides under specific physiological conditions. While most of the S-nitrosothiol compounds are unstable, S-Nitrosoglutathione is exceptionally stable....

Si-DMA for Mitochondrial Singlet Oxygen Imaging MT05, MT05-10, Si-DMA for Mitochondrial Singlet Oxygen Imaging,
Item #: MT05 -

Storage Condition : Store at 0-5oC and protect from light Product Description Singlet oxygen (1O2) is one of the Reactive Oxygen Species (ROS). 1O2 is known to be a cause of spots and wrinkles of the skin due to its very strong oxidizing potential. In the field of cancer research, 1O2 is of a particular importance because of its key role in photodynamic therapy (PDT), an emerging anticancer treatment using photoirradiation and photosensitizers. For the detection of 1O2, the existing singlet...

SIN-1 SIN-1, 3-(4-Morpholinyl)sydnonimine, hydrochloride [CAS: 16142-27-1]
Item #: S264 -

Chemical Name: 3-(4-Morpholinyl)sydnonimine, hydrochloride CAS: 16142-27-1Appearance: White or slightly yellowish needles or crystalline powderMW: 206.63, C6H11ClN4O2Storage Condition: -20ºC Shipping Condition: protect from light and moisture with blue ice or dry iceProduct DescriptionSIN-1, a metabolite of the vasodilator molsidomine, is utilized to separately estimate the effectiveness of NO and peroxynitrite with other NO donors. SIN-1 spontaneously decomposes in the presence of...

SOD Assay Kit-WST SOD Assay Kit-WST, Superoxide dismutase, ROS, Oxidative stress, Superoxide anion, Radical, NBT, NBT method, SOD1, SOD2, WST-1, IC50, Cu/Zn-SOD, Xanthine, Xanthine oxidase, SOD inhibition activity, Superoxid, NBT
Item #: S311 -

Contents of the Kit: 500 tests WST solution :5 ml, 1 bottle Enzyme solution :100 μl, 1 vial Buffer solution :100 ml, 1 bottle Dilution buffer :50 ml,1 bottle Storage Condition: 0-5°CShipping Condition: ambient temperature or with blue iceRequired Equipment and MaterialsMicroplate reader with 450 nm filter, 37ºC incubator, 96-well clear plate, 10 μl and 200 μl adjustable pipettes, multi-channel pipetteProduct DescriptionSuperoxide dismutase (SOD), which catalyzes the dismutation of the...

SPiDER-ßGal SPiDER-ßGal, SG02, SG02-10,
Item #: SG02 -

Storage Condition : 0-5oC Shipping Condition : ambient temperature CAS# : 1824699-57-1 Product Description The gene of β-galactosidase from E. coli is widely used as a reporter gene assay marker. Although X-gal is well known reagent to detect β-galactosidase in cell or tissue samples, the assay using these reagents require to fix cells or tissues due to the poor cell-permeability. In addition, so far developed the assay using fluorescence reagents cannot clearly differentiate...

Spy-LHP Spy-LHP, 2-(4-Diphenylphosphanyl-phenyl)-9-(1-hexyl-heptyl)-anthra[2,1,9-def,6,5,10-d’e’f’]diisoquinoline- 1,3,8,10-tetraone
Item #: S343 -

Chemical Name: 2-(4-Diphenylphosphanyl-phenyl)-9-(1-hexyl-heptyl)-anthra[2,1,9-def,6,5,10-d’e’f’]diisoquinoline-1,3,8,10-tetraoneAppearance: Reddish black crystalline powder or solidPurity: ≥90.0% (HPLC)MW: 832.96, C55H49N2O4PStorage Condition: ambient temperature, protect from lightShipping Condition: ambient temperatureProduct DescriptionSpy-LHP is a newly developed fluorescent probe for live cell imaging of phospholipid peroxide. There are several detection methods available for lipid...

Total Glutathione Quantification Kit Total Glutathione Quantification Kit
Item #: T419 -

Contents of the Kit Enzyme solution  : 50 μl, 1 vial Substrate  : 2 vials Buffer solution  : 50 ml, 1 bottle Co-enzyme (lyophilized)  : 2 vials Standard GSH (lyophilized) : 1 vialStorage Condition: 0-5ºCShipping Condition: ambient temperature or with blue iceRequired Equipment and Materialsmicroplate reader with 405 or 415 nm filter, 37ºC incubator, 96-well clear plate, 20 μl and 200 μl adjustable pipettes, multi-channel pipetteProduct DescriptionGlutathione (GSH) is...