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Dithiobis(succinimidyl hexanoate)

Item # Unit Size
D539-12
50 mg

For Research Use Only Products

Application: SAM preparation, amine reactive group coating

Chemical Name: Dithiobis(1-succinimidyl hexanoate)

Appearance: White powder
Purity: ≥90.0% (HPLC)
MW: 488.58, C20H28N2O8S2

Storage Condition: 0-5ºC, protect from moisture
Shipping Condition: ambient temperature
MSDS

Structural Formula


Product Description of Succinimidyl Alkanedisulfides
Succinimidyl ester-terminated alkyldisulfides are amine-reactive analogs of carboxyalkyldisulfide. They are utilized for the modification of a gold surface to introduce amine-reactive sites on the surface. It is possible to use this technique for protein chips and various sensors. There is no need to use coupling agents because these compounds are already activated. Wagner and others characterized dithiobis(succinimidyl undecanoate) SAMs on a gold substrate by scanning tunneling microscopy (STM), radiolabeling and in situ AFM imaging. The densely packed and highly reactive surfaces allowed them to easily immobilize amino acids and proteins.
Example of Solvents
10 mmol/L (Chloroform, Dichloromethane, Tetrahydrofuran, Acetonitrile, Ethyl acetate, Dimethyl sulfoxide, Dimethyl formamide)

<Caution>
When it is difficult to take out all the powder from the container,
please add the solvent into a container and dissolve it before its use.
1) E. Delamarche, G. Sundarabaru, H. Biebuyck, B. Michel, Ch. Gerber, H. Sigrist, H. Wolf, H. Ringsdorf, N. Xanthopoulos and H. J. Mathieu, Immobilization of Antibodies on a Photoactive Self-Assembled Monolater on Gold, Langmuir, 1996, 12, 1997.
2) P.Wager, F. Zaugg, P. Kernen, M. Hegner and G. Semenza, ρEfunctionalized self-assembled monolayers chemisorbed on ultraflat Au(111) surfaces for biological scanning probe microscopy in aqueous buffers, J. Vac. Sci. Technol. B, 1996, 14, 1466.