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Item # Unit Size
100 g

For Research Use Only Products

Chemical Name: O,O'-Bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid
CAS: 67-42-5

Appearance: White crystalline powder
Purity: ≥97.0% (Titration)
MW: 380.35, C14H24N2O10

Storage Condition: ambient temperature
Shipping Condition: ambient temperature

Calcium Chelation

Product Description
EGTA is the most widely used calcium- selective chelator. The calcium complex of EGTA is 100,000 times more stable than its Mg complex. It is utilized to prepare calcium buffers and control the calcium ion concentration.

Table of Stability Constants
1) C. L. Luke, et al., Photometric Determination of Magnesium in Electronic Nickel. Anal Chem. 1954;26:1778-1780.
2) F. S. Sadek, et al., Visual EGTA Titration of Calcium in Thepresence of Magnesium. Talanta. 1959;2:38-51.
3) R. Pribil, et al., Contributions to the Basic Problems of Complexometry-XX Determination of Calcium and Magnesium. Talanta. 1966;13:233-236.
4) T. Tatsumi, et al., Hypochlorous Acid Mobilizes Intracellular Zinc in Isolated Rat Heart Myocytes. J Mol Cell Cardiol. 1994;26:471-479.
5) H. Ohata, et al., Confocal Imaging Analysis of ATP-Induced Ca2+ Response in Individual Endothelial Cells of the Artery in Situ. Am J Physiol. 1997;272:C1980-C1987.
6) I. Sakabe, et al., Induction of Apoptosis in Neuro-2A Cells by Zn2+ Chelating. Cell Struct Funct. 1998;23:95-99.