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Hydroxy-EG6-hexadecanethiol

Item # Unit Size
H396-10
10 mg

For Research Use Only Products

Application: SAM preparation, dilution of functional alkanethiols

Chemical Name: 16-Mercaptohexadecanol hexathyleneglycol ether

Appearance: White or slightly yellow solid
Purity: ≥95.0% (HPLC)
Solubility: 10 mmol/L (Ethyl alcohol, Methyl alcohol, Chloroform)
MW: 538.82, C28H58O7S

Storage Condition: -20oC, protect from metal
Shipping Condition: with blue ice
MSDS

Structural Formula


Product Description
Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Hydroxy-EGn-undecanethiol has 3 or 6 ethylene glycol units, 11 carbon atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface that is suitable for biomateriallabelings on the surface. This is due to the improvement of hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays. Hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute Carboxyl -SAM or Amino-SAM according to the density of the molecules be introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin and cytochrome C.
Example of Solvents
10 mmol/L (Ethyl alcohol, Methyl alcohol, Chloroform)

<Caution>
When it is difficult to take out all the powder from the container,
please add the solvent into a container and dissolve it before its use.
1) C. Pale-Grosdemange, E. S. Simon, K. L. Prime and G. M. Whitesides, Anal. Chem., 1999, 71, 777.
2) M. Kyo, K. Usui-Aoki, H. Koga, Anal. Chem, 2005, 77, 7115.