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-SulfoBiotics- Sodium sulfide (Na2S)

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For Research Use Only Products

Storage Condition :  0-5℃,moisture sensitive
Shipping Condition : ambient
Purity : ≥97.0%
Chemical name: Sodium sulfide  
M.W.: 78.04 
CAS#: 1313-82-2

Product Description:

It has been recognized that hydrogen sulfide (H2S) has an important role as a physiological active substance for vasodilation, cytoprotection, and modulation of insulin secretion. H2S is considered as a gaseous molecule such as NO and CO. However, around 80% of the total sulfide exists as hydrogen sulfide anion (HS-) under physiological condition, since the pKa is about 7 (Fig. 1). In addition, H2S easily converts to various biochemical molecules such as persulfides and polysulfides, which react with sulfhydryl moieties in a living body. The functional mechanism of H2S has not been well understood.Sodium sulfide (Na2S) has been widely used as a H2S donor. Na2S is readly decomposed and release H2S when Na2S is dissolved in H2O.

1) R. Greiner, Z. Palinkas, K. Basell, D. Becher, H. Antelmann, P. Nagy and T. P. Dick, “Polysulfides link H2S to protein thiol oxidation”, Antioxid. Redox Signal., 2013, 19, 1749.
2) N. S. Lawrence, J. Davis and R. G. Compton, “Analytical strategies for the detection of sulfide: a review”, Talanta, 2000, 52, 771.